100 Best Selling and Most Prescribed Branded Drugs 2014-2015

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The hypothyroid drug levothyroxine (Synthroid, AbbVie) was the most prescribed drug in the United States, and the arthritis drug adalimumab (Humira, Abbott Laboratories) was the best-selling drug through March of this year, according to recent data.

Research firm IMS released a rolling 12-month history of prescription numbers and total sales from April 2014 through March 2015.

Levothyroxine had about 21.6 million prescriptions, followed by cholesterol-lowering drug rosuvastatin (Crestor, AstraZeneca), at about 21.5 million prescriptions; asthma medication albuterol (Ventolin HFA, GlaxoSmithKline), at about 18.2 million prescriptions; proton pump inhibitor esomeprazole (Nexium, AstraZeneca), at about 15.3 million prescriptions; and asthma medication fluticasone propionate/salmeterol (Advair Diskus, GlaxoSmithKline), at about 13.8 million prescriptions.

The remaining top 10 most prescribed drugs for the period (in order) were the insulin glargine injection (Lantus Solostar, sanofi-aventis), the attention-deficit drug lisdexamfetamine dimesylate (Vyvanse, Shire), the antiepileptic drug pregabalin (Lyrica, Pfizer), the chronic obstructive pulmonary disease medication tiotropium bromide (Spiriva Handihaler, Boehringer Ingelheim Pharmaceuticals), and the diabetes drug sitagliptin (Januvia, Merck)

Top Sellers

The arthritis drug adalimumab (Humira, Abbott Laboratories) had sales of about $8.3 billion, followed by the antipsychotic medication aripiprazole (Abilify, Otsuka Pharmaceutical) at $8 billion, the hepatitis C drug sofosbuvir (Sovaldi, Gilead Sciences) at $7 billion, the cholesterol-lowering drug rosuvastatin (Crestor, AstraZeneca) at $6 billion, and the arthritis drug etanercept (Enbrel, Amgen) at almost $6 billion.

The remaining top 10 drugs in sales were the hepatitis C drug ledipasvir/sofosbuvir (Harvoni, Gilead), the proton pump inhibitor esomeprazole (Nexium, AstraZeneca), the asthma medication fluticasone propionate/salmeterol (Advair Diskus, GlaxoSmithKline), the insulin glargine injection (Lantus Solostar, sanofi-aventis), and the arthritis drug infliximab (Remicade, Centocor).

Top 100 Prescriptions, Volume

Drug Name Sales
Synthroid 21,561,481
Crestor 21,478,776
Ventolin HFA 18,203,939
Nexium 15,298,228
Advair Diskus 13,776,325
Lantus Solostar 10,939,840
Vyvanse 10,413,999
Lyrica 10,022,365
Spiriva Handihaler 9,635,935
Januvia 9,148,946
Lantus 9,145,153
Abilify 9,099,978
Symbicort 8,265,594
Tamiflu 8,025,275
Cialis 7,472,719
Viagra 7,104,074
Suboxone 6,985,631
Zetia 6,925,137
Xarelto 6,739,752
Bystolic 6,461,435
Celebrex 6,449,730
Nasonex 6,432,382
Namenda 5,961,360
Flovent HFA 5,736,650
Oxycontin 5,347,532
Diovan 5,224,025
Thyroid 5,128,576
Voltaren Gel 5,123,676
Nuvaring 4,917,514
Afluria 4,650,167
Dexilant 4,620,902
Benicar 4,483,555
Proventil HFA 4,385,623
Humalog 4,209,193
Novolog Flexpen 4,179,914
Novolog 3,968,615
Vesicare 3,686,182
Premarin 3,462,987
Benicar HCT 3,352,383
Lo Loestrin Fe 3,335,659
Lumigan 3,298,208
Namenda XR 3,157,234
Humalog Kwikpen 3,043,015
Janumet 3,027,293
Pataday 2,905,818
Ortho-Tri-Cy Lo 28 2,900,301
Travatan Z 2,861,717
Combivent Respimat 2,846,891
Toprol-XL 2,811,156
Pristiq 2,769,837
Invokana 2,711,901
Minastrin 24 Fe 2,555,803
Strattera 2,418,649
Seroquel XR 2,390,205
Vytorin 2,384,517
Focalin XR 2,334,004
Dulera 2,307,692
Levemir Flexpen 2,283,328
Zostavax 2,279,662
Avodart 2,271,799
Pradaxa 2,257,507
Chantix 2,208,377
Eliquis 2,179,340
Humira 2,173,082
Levemir Flextouch 2,164,191
Levemir 2,100,856
Victoza 3-Pak 2,078,630
Combigan 1,909,750
Exelon 1,825,705
Tradjenta 1,744,708
Premarin Vaginal 1,738,728
Enbrel 1,691,819
Onglyza 1,691,615
Ranexa 1,661,050
Truvada 1,651,083
Welchol 1,644,996
Linzess 1,639,652
Latuda 1,635,230
Alphagan P 1,483,322
Viibryd 1,425,156
Effient 1,406,934
Norvir 1,376,523
Amitiza 1,371,937
Azor 1,338,802
Advair HFA 1,310,993
Uloric 1,293,249
Lotemax 1,245,330
Myrbetriq 1,230,040
Asmanex Twisthaler 1,219,923
Epiduo 1,212,887
Xopenex HFA 1,204,025
Durezol 1,189,206
Patanol 1,181,134
Atripla 1,147,295
Aggrenox 1,144,739
Exforge 1,134,532
Humulin R 1,110,123
Carafate 1,110,008
Novolog Flxpen Mix 70/30 1,069,219
Relpax 1,035,265
Total 426,157,198

 

Top 100 Prescriptions

Product Sales $
Humira $8,290,106,091
Abilify $7,995,192,015
Sovaldi $6,957,331,432
Crestor $5,958,997,432
Enbrel $5,953,627,734
Harvoni $5,398,133,616
Nexium $5,394,307,899
Advair Diskus $4,789,231,826
Lantus Solostar $4,770,782,304
Remicade $4,614,448,608
Copaxone $4,182,899,363
Neulasta $3,922,031,456
Januvia $3,614,160,358
Lantus $3,566,103,749
Rituxan $3,544,238,274
Spiriva Handihaler $3,376,228,289
Lyrica $3,266,031,544
Tecfidera $3,099,936,398
Atripla $2,978,855,683
Avastin $2,965,061,371
Truvada $2,578,983,746
Gleevec $2,503,368,238
Epogen $2,473,399,804
Oxycontin $2,465,943,666
Symbicort $2,360,996,657
Herceptin $2,298,726,899
Xarelto $2,284,828,697
Vyvanse $2,160,713,724
Zetia $2,084,878,153
Novolog Flexpen $2,057,726,217
Celebrex $1,910,900,690
Lucentis $1,846,895,026
Olysio $1,841,298,803
Humalog $1,777,573,187
Novolog $1,682,412,487
Stelara $1,681,699,491
Tysabri $1,567,603,895
Victoza 3-Pak $1,551,256,216
Stribild $1,521,776,680
Humalog Kwikpen $1,502,106,919
Gilenya $1,473,842,883
Namenda $1,467,285,489
Cialis $1,444,220,727
Suboxone $1,425,290,432
Prevnar 13 $1,396,162,844
Viagra $1,352,420,339
Seroquel XR $1,348,914,720
Avonex Pen $1,265,072,458
Latuda $1,255,720,111
Renvela $1,238,809,132
Alimta $1,228,896,729
Levemir Flextouch $1,191,214,618
Janumet $1,186,223,316
Prezista $1,180,847,342
Flovent HFA $1,164,131,971
Nasonex $1,152,398,925
Orencia $1,143,314,317
Dexilant $1,112,428,137
Zytiga $1,070,295,487
Tamiflu $1,062,635,381
Invega Sustenna $1,060,318,741
Avonex $1,056,780,770
Vesicare $1,039,389,101
Revlimid $1,029,532,746
Isentress $1,029,298,768
Synthroid $1,022,330,768
Sensipar $981,745,658
Benicar $980,584,320
Diovan $976,553,203
Invokana $970,548,874
Complera $959,404,062
Procrit $952,064,680
Xolair $947,519,208
Xgeva $931,245,431
Combivent Respimat $911,002,564
Levemir Flexpen $897,404,938
Cimzia $882,246,079
Reyataz $864,112,503
Pradaxa $861,575,903
Afinitor $847,476,278
Aranesp $840,688,834
Ventolin HFA $836,444,530
Bystolic $834,232,105
Neupogen $809,055,804
Gardasil $806,914,360
Levemir $804,193,630
Sprycel $797,720,901
Xifaxan $767,934,882
Strattera $762,979,130
Benicar HCT $759,903,978
Prolia $757,969,582
Namenda XR $752,841,699
Vytorin $749,130,132
Eliquis $746,321,783
Yervoy $743,127,508
Sandostatin Lar $738,303,189
Pristiq $737,859,917
Welchol $723,662,256
Zostavax $712,431,619
Treanda $706,972,581
Total $194,540,743,010
 

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